Defining disease-associated T and B cell repertoires in chronic inflammatory diseases
Principle Investigators:
Prof. Dr. Sebastian Zeißig (Department of Internal Medicine I)
Prof. Dr. Ralf Ludwig (Institute of Experimental Dermatology)
Prof. Dr. Rudolf Manz (Institute for Systemic Inflammation Research)
PD Dr. Kathrin Kalies (Institute of Anatomy)
From primary gene defect(s) to molecular mechanisms leading to hypergammaglobulinemia and therapy resistance of antibody-secreting plasma cells in systemic lupus erythematosus (EXC 306/2 project J, TP2)
Principle Investigators:
Prof. Dr. Rudolf Manz (Institute for Systemic Inflammation Research)
Prof. Dr. Saleh Ibrahim (Department of Dermatology)
The glycosylation pattern of IgG autoantibodies determines the severity of autoimmune diseases (EXC 306/2)
Principle Investigators:
Prof. Dr. Marc Ehlers (Institute for Systemic Inflammation Research)
Prof. Dr. Dr. Enno Schmidt (Department of Dermatology)
Prevention of fibrosis following epithelial-to-mesenchymal transition / inflammasome NLRP3 interactions by acid sphingomyelinase inhibition and phosphatidylglycerol substitution in neonatal acute respiratory distress syndrome.
Principle Investigators:
Prof. Dr. Krause (Clinics for Gen. Pediatrics and Ped. Cardiology)
Prof. Dr. Schütze (Institute of Immunology, Kiel)
Prof. Dr. Fehrenbach (Experimental Pneumology, Borstel)
PD. Dr. Schromm (Immunobiophysics, Borstel)
Key players of early inflammatory response: Functional plasticity and epigenetic profiling of human gd T-cells and NKT cells.
Principle Investigators:
Prof. Dr. Kabelitz (Institute of Immunology, Kiel)
Prof. Dr. Zeißig (I. Medical Clinic, Kiel)
Dr. O. Ammerpohl (Institute for Human Genetics, Kiel)
